Engage with Cutting Edge Discovery and Optimisation

Increasing emphasis is being placed on the discovery and lead optimisation stage of drug development. This ensures that the development of unsuitable drug candidates is stopped at the earliest stage possible, and the most promising candidates are moved quickly into full preclinical development.

Bespoke safety and efficacy models can be developed based on your requirements so that you have the critical information required to make better decisions on the potential of your preclinical candidates.

Maccine is also developing imaging capabilities that will further increase the relevancy and accuracy of your data.

Our discovery services include:

• Innovative NHP Efficacy and Surgical Models
• Pharmacokinetic/Pharmacodynamic Screening Studies
• Investigative Toxicity Evaluations

Reliable Safety Assessment

Accelerate your Drug Development

Maccine’s GLP safety assessment services provide you with the support you need for your regulatory filings. We perform studies in rodent and non-human primate test species and offer a variety of administration routes.

We offer:

• Dose Range Finding
• Maximum Tolerated Dosing
• Acute toxicology
• Sub-Chronic/Chronic Toxicity
• Safety Pharmacology

We support a variety of dose routes and schedules, including:

• Oral (gavage and capsule)
• Parenteral (intravenous, subcutaneous, intraperitoneal, intramuscular)